ANALISIS KADAR ASAM URAT WANITA DEWASA USIA 40-60 TAHUN SETELAH KONSUMSI JUS TOMAT-JERUK NIPIS

Authors

  • Iffania Karimatur Rasyada Poltekkes Kemenkes Semarang
  • Mohammad Jaelani Poltekkes Kemenkes Semarang
  • Wiwik Wijaningsih Poltekkes Kemenkes Semarang

DOI:

https://doi.org/10.31983/jrg.v5i2.4277

Keywords:

Levels of uric acid, Tomato Juice, Lime, Adult Women

Abstract

Background  : The prevalence of gout arthritis in Indonesia there is no definitive data. Epidemiological surveys conducted in Bandungan, Central Java on WHO-COPCORD cooperation on 4,683 samples aged between 15-65 years found that the prevalence of gout arthritis in women was 11.7% (Darmawan, 2003). The use of drugs aimed at lowering uric acid levels can cause some side effects, such as nausea, vomiting, and diarrhea so that the level of adherence will decrease (M. Adib, 2011).

 

Objective  : To analalysis determine the effect of tomato-lemon juice on uric acid level of adult women aged 40-60 years.

 

Methods  : A true experimental research design type with a randomized pretest-posttest control group design. Number of respondents 20 treatments and 18 controls. Intervention was performed for 21 days with the measurement of uric acid at before and after intervention. The test used is paired t test, independent t test and ANCOVA with 95% confidence degree.

 

Result  : paired t test showed no difference of pre and post in treatment group (p>0,05). Analysis of the effect on the group with normal uric acid category p = 0.655, in the pre hyperuricemia group p = 0.235 and in hyperuricemia p = 0.221. There was a decrease in uric acid levels by 0.26 mg / dl in hyperuricemia but not significant. ANCOVA results show that juice will give significant effect if controlled with initial uric acid level (p = 0,00).

 

Conclusion  : There was no effect of tomato-lime juice consumption on uric acid levels, but there was a decrease of 0.26 in the hyperuricemia group but not significant. It is recommended to do further research on hyperuricemia.

Author Biographies

Iffania Karimatur Rasyada, Poltekkes Kemenkes Semarang

Jurusan Gizi

Mohammad Jaelani, Poltekkes Kemenkes Semarang

Jurusan Gizi

Wiwik Wijaningsih, Poltekkes Kemenkes Semarang

Jurusan Gizi

References

1. Misnadiarly.. Rematik : Asam Urat, Hiperurisemia, Artritis Gout. Edisi 1.Pustaka Obor Populer. Jakarta. 2007. p.20
2. Damayanti, D. Sembuh Total Diabetes, Asam Urat, Hipertensi Tanpa Obat. Pinang Merah Publisher. Yogyakarta. 2013. p. 73-75.
3. Khomsan, Ali dan Yuni Harlinawati. Terapi Jus Untuk Rematik dan Asam Urat. Puspaswara. Depok. 2008. p.4.
4. Adib, M. Pengetahuan Praktis Ragam Penyakit Mematikan yang Paling Sering Menyerang Kita. BukuBiru. Jogjakarta. 2011. p.9-16.
5. Vinha, A.F., Barreira, S.V., Costa, A.S., Alves, R.C. and Oliveira, M.B.P. “Pre-meal tomato (Lycopersicon esculentum) intake can have anti-obesity effects in young women?”. International journal of food sciences and nutrition. 2014. 65(8), pp.1019-1026.
6. Hasanah, N.L.N.,"Perbandingan antara Pemberian Allopurinol dan Air Perasan Buah Jeruk Nipis (Citrus Aurantifolia) Terhadap Penurunan Kadar Asam Urat pada Mencit Model Hiperurisemia" (Doctoral dissertation, Fakultas Kedokteran (UNISBA). 2016.
7. Kanbara, A., Hakoda, M. and Seyama, I. “Urine alkalization facilitates uric acid excretion”. Nutrition journal. 2010. 9(1), p.45.
8. Kanbara, A, Miura, Y., Hyogo, H., Chayama, K. and Seyama, I. “Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid”. Nutrition journal. 2012. 11(1), p.39.
9. NutriSurvey. 2007. NutriSurvey for Windows. http// www.nutrisurvey.de atau [email protected]. 8 Mei 2017 (05:16).\
10. Kemenkes RI. Peraturan Menteri Kesehatan Republik Indonesia Nomor 75 Tahun 2013 Tentang Angka Kecukupan Gizi yang Dianjurkan Bagi Bangsa Indonesia. Jakarta: Kementerian Kesehatan RI. 2013.
11. Fitriyah, P.C., Juanita, F. and Mudayan, A. “Hubungan Obesitas Dengan Kadar Asam Urat Darah Di Dusun Pilanggadung Kecamatan Tikung Kabupaten Lamongan”. Jurnal Surya. 2014. Vol.02, No.IX
12. Kertia, Nyoman. Asam Urat: Benarkah Hanya Menyerang Laki-laki?. PT. Bentang Pustaka. Yogyakarta. 2009. p.11-12
13. Herlianty, MP. “Faktor Gizi Sebagai Determinan Hiperurisemia”. Konas XII Persagi. Persatuan Ahli Gizi Indonesia. 2002. p.152-155
14. Setyoningsih, R. and Setyoningsih, R.. “Faktor-Faktor yang Berhubungan dengan Kejadian Hiperurisemia pada Pasien Rawat Jalan RSUP Dr. Kariadi Semarang” (Doctoral dissertation, Program Studi Ilmu Gizi). 2009.
15. National Institute Health. Diet for Kidney stone prevention. National Kidney anda Urologic Disease Information. February 2013; 13: 1-3.
16. Zhang, M.L., Gao, Y.X., Wang, X., Chang, H. and Huang, G.W.“Serum Uric Acid And Appropriate Cutoff Value For Prediction Of Metabolic Syndrome Among Chinese Adults”. Journal of clinical biochemistry and nutrition. 2013. 52(1), pp.38-42
17. Hidayat, Rudy. “Gout dan Hiperurisemia”. Medicinus. 2009. 22 (1), pp. 47-50.
18. Gliozzi, M., Malara, N., Muscoli, S. and Mollace, V.“The Treatment of Hyperuricemia”. International journal of cardiology. 2016. 213, pp.23-27.
19. Indra P.H, Denny. Super Foods: Sehat dan Bugar dengan Beragam Pangan Fungsional Sehari-hari. Flash book. Jogjakarta. 2012. p.40.
20. Mo, S.F., Zhou, F., Lv, Y.Z., Hu, Q.H., Zhang, D.M. and Kong, L.D. “Hypouricemic Action Of Selected Flavonoids In Mice: Structure–Activity Relationships”. Biological and Pharmaceutical Bulletin. 2007. 30(8), pp.1551-1556.

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Published

2017-11-12

Issue

Vol. 5 No. 2 (2017): November (2017)

Section

Articles

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This is an Open Access article distributed under the terms of the CC BY-SA 4.0 License