Comparison of The Antibacterial Activity of Bentonite and Amoksisilin Against Streptococcus Mutans Causes of Caries
DOI:
https://doi.org/10.31983/jkg.v10i2.10867Kata Kunci:
bentonite, amoksisilin, antibacterial, StreptococcusAbstrak
Streptococcus mutans is a normal flora bacteria in the oral cavity. Streptococcus mutans colonizes the oral cavity during the eruption of the first teeth, which in turn causes the teeth to experience caries. Bentonite is a clay consisting of the mineral smectite, especially montmorillonite. Montmorillonite is a member of smectite with the chemical formula (Al2O3 4 SiO2 x H2O). The high cation exchange capacity and fine particle size can inhibit bacterial growth. This study aims to compare the antibacterial activity of bentonite and amoksisilin against Streptococcus mutans. Materials and research methods divide the bentonite solution into five groups with concentrations of 5%, 10%, 20%, 40%, and 100%, and one group of amoksisilin and one control group. The solution was tested for antibacterial activity by diffusion on blood agar against Streptococcus mutans. The results showed that all bentonite solution groups differed from the amoksisilin group (p < 0.05). Meanwhile, the antibacterial activity of the bentonite solution group was no different from the negative control group (p > 0.05). The conclusion from this study was that there was a difference in antibacterial activity between the bentonite and amoksisilin groups, where bentonite did not show inhibition of the growth of Streptococcus mutans bacteriaReferensi
A. Simón-Soro and A. Mira, “Solving the etiology of dental caries,†Trends in Microbiology, vol. 23, no. 2. 2015. doi: 10.1016/j.tim.2014.10.010.
S. D. Safela, E. Purwaningsih, and Isnanto, “Systematic Literature Review: Faktor yang Mempengaruhi Karies Gigi pada Anak Sekolah Dasar,†Jurnal Ilmiah Keperawatan Gigi, vol. 2, no. 2, 2021.
A. Syah, R. A. Ruwanda, and A. Basid, “Faktor-Faktor Yang Berhubungan Dengan Status Karies Gigi Pada Anak Sekolah Min 1 Kota Banjarmasin,†Jurnal Kesehatan Indonesia, vol. 9, no. 3, 2019, doi: 10.33657/jurkessia.v9i3.184.
M. Akheel and S. Bedi, “Role of the oral bacteria in dental caries,†International Journal of Students Research, vol. 3, no. 1, p. 31, 2013, doi: 10.4103/2230-7095.113835.
J. Y. Friedman, “The Role of Streptococcus Mutans in the Formation of Dental Caries: An Ecological Perspective,†The Science Journal of the Lander College of Arts and Sciences, vol. 5, no. 1, 2011.
Endriani, R., Siregar, F. M., Rafni, E., Azhari, R. K., & Jefrizal, J. , “Identifikasi Gen Kariogenik Glukosiltransferase Streptococcus Mutans Pada Pasien Karies Gigi Identification of Streptococcus Mutans Cariogenic Gene Glucosyltransferase (Gtf) in Dental Caries Patientsâ€. Jurnal Kedokteran Gigi Universitas Padjadjaran, 33(1), 14-18., 2021. doi: 10.24198/jkg.v33i1.30397.
H. K. Kuramitsu, “ The Virulence Properties of Streptococcus mutans ,†in Gram-Positive Pathogens, 2014. doi: 10.1128/9781555816513.ch28.
D. G. S. Burch and D. Sperling, “Amoxicillin—current use in swine medicine,†Journal of Veterinary Pharmacology and Therapeutics, vol. 41, no. 3. 2018. doi: 10.1111/jvp.12482.
B. A. de Marco, J. S. H. Natori, S. Fanelli, E. G. Tótoli, and H. R. N. Salgado, “Characteristics, Properties and Analytical Methods of Amoxicillin: A Review with Green Approach,†Critical Reviews in Analytical Chemistry, vol. 47, no. 3. 2017. doi: 10.1080/10408347.2017.1281097.
E. T. Enan, A. A. Ashour, S. Basha, N. H. Felemban, and S. M. F. Gad El-Rab, “Antimicrobial activity of biosynthesized silver nanoparticles, amoxicillin, and glass-ionomer cement against Streptococcus mutans and Staphylococcus aureus,†Nanotechnology, vol. 32, no. 21, 2021, doi: 10.1088/1361-6528/abe577.
D. Guo, Q. Xia, H. Dong, X. Wang, Q. Zeng, and Y. Zhao, “Antibacterial clay minerals: Research advances and outlook,†Earth Science Frontiers, vol. 29, no. 1. 2022. doi: 10.13745/j.esf.sf.2021.7.20.
P. P. Singh and Ambika, “Bentonite: A versetile clay,†in Bentonite: Characteristics, Uses and Implications for the Environment, 2015.
C. Ruskandi, A. Siswanto, and R. Widodo, “Karakterisasi Fisik dan Kimiawi Bentonite Untuk Membedakan Natural Sodium Bentonite dengan Sodium Bentonite Hasil Aktivasi,†Polimesin, vol. 18, no. 01, 2020.
M. Moosavi, “Bentonite clay as a natural remedy: A brief review,†Iranian Journal of Public Health, vol. 46, no. 9. 2017.
D. Kimia, F. Mipa, U. G. Mada, and S. U. Yogyakarta, “Material Cuo/Bentonit Sebagai Bahan Antibakteri Escherichia Coli,†Bimipa, vol. 25, no. 3, pp. 216–223, 2019.
Martsouka, F., Papagiannopoulos, K., Hatziantoniou, S., Barlog, M., Lagiopoulos, G., Tatoulis, T., & Papoulis, D., “The antimicrobial properties of modified pharmaceutical bentonite with zinc and copper,†Pharmaceutics, vol. 13, no. 8, 2021, doi: 10.3390/pharmaceutics13081190.
Lemos, J. A., Palmer, S. R., Zeng, L., Wen, Z. T., Kajfasz, J. K., Freires, I. A., & Brady, L. J, “ The Biology of Streptococcus mutans ,†Microbiol Spectr, vol. 7, no. 1, 2019, doi: 10.1128/microbiolspec.gpp3-0051-2018.
L. D. Maxim, R. Niebo, and E. E. McConnell, “Bentonite toxicology and epidemiology – a review,†Inhalation Toxicology, vol. 28, no. 13. 2016. doi: 10.1080/08958378.2016.1240727.
Sjamsiah, S., Arifuddin, A., Masri, M., Sappewali, S., Islamiah, I., Hamrullah, H., & Nesti, E, “Sifat Fisika Kimia Tanah dan Daya Hambatnya terhadap Bakteri Air Liur Anjing Liar,†Al-Kimia, vol. 7, no. 1, 2019.
Dwi Warna Aju Fatmawati, “Hubungan Biofilm Streptococcus Mutans Terhadap Resiko Terjadinya Karies Gigi,†Stomatognatic(J.K.G Unej) Vol. 8 No. 3, 2011: 127-130, vol. 46, no. 4, 2014.
C. A. J. Appelo, “A Review of Porosity and Diffusion in Bentonite,†POSIVA Working report 29, vol. 29, no. October, 2013.
Unduhan
Diterbitkan
Terbitan
Bagian
Lisensi
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. that allows others to share — copy and redistribute the material in any medium or format and adapt — remix, transform, and build upon the material for any purpose, even commercially with an acknowledgment of the work's authorship and initial publication in this journal.
