Total SGOT, SGPT and Bilirubin Levels in Pulmonary Tuberculosis Patients

Titan Melina Putri, Widodo Widodo

Abstract


Tuberculosis is an infectious infection caused by Mycobacterium tuberculosis. Anti Tuberculosis drug therapy given has side effects, one of which is hepatotoxicity.. The purpose of this study was to describe the levels of SGOT, SGPT, and total bilirubin in pulmonary tuberculosis patients based on the characteristics of gender and age. This type of research is descriptive observational with a case study approach. Data retrieval using purposive sampling of 120 patients was carried out by analyzing data on medical records. The results of the study in the intensive stage of treatment showed an increase in SGOT for 12 males and females an average of 71 U/L and 93 U/L. The SGPT of 12 men and 14 women averaged 86 U/L and 92 U/L. Total bilirubin in 10 men and 12 women averaged 1.58 mg/dl and 1.68 mg/dl, respectively. The increase in SGOT in 15 patients 26-45 years, 8 patients 46-65 years, and 2 patients >65 years averaged 79 U/L, 70 U/L, and 97 U/L. SGPT occurred in 15 patients 26-45 years, 8 patients 46-65 years, and 3 patients >65 years with mean levels of 82 U/L, 97 U/L, and 96 U/L. Total bilirubin occurred in 15 patients 26-45 years, 5 patients 46-65 years, and 2 patients >65 years with mean levels of 1.72 mg/dl, 1.38 mg/dl, and 1.57 mg/dl. , whereas in the advanced stage of treatment, all patients had normal levels of SGOT, SGPT, and total bilirubin with an average of 27 U/L, 29 U/L, and 0.41 mg/dl.

Keywords


Tuberculosis ; OAT ; SGOT ; SGPT ; Total Bilirubin

References


Adriani, W., Fauzi, Z. A., dan Rahayu, W. (2016). Gambaran nilai sgot dan sgpt tuberkulosis paru yang dirawat inap di RSUD Arifin Achmad Provinsi Riau tahun 2013.

Aminah, S. (2013). Perbedaan Kadar SGOT , SGPT , Ureum , dan Kreatinin Pada Penderita TB Paru Setelah Enam Bulan Pengobatan. Jurnal Analis Kesehatan.

Clarasanti, I., Wongkar, M. C. P., dan Waleleng, B. J. (2016). Gambaran enzim transaminase pada pasien tuberkulosis paru yang diterapi dengan obat-obat anti tuberkulosis di RSUP Prof. Dr. R. D. Kandou Manado. E-CliniC. https://doi.org/10.35790/ecl.4.1.2016.12102

Dewi, B. D. N. (2019). Diabetes Mellitus & Infeksi Tuberkulosis. Andi.

Dinas Kesehatan Jawa Tengah. (2018). profil kesehatan jawa tengah 2018. In jaJournal of Visual Languages & Computing.

Firdayanti, F. (2019). Gambaran Kadar Bilirubin Total pada Penderita Tuberkulosis Paru dengan Terapi Obat Anti Tuberkulosis (Oat) di Puskesmas Poasia Kota Kendari. Jurnal Kesehatan Vokasional. https://doi.org/10.22146/jkesvo.44487

Juliarta, I. G., Mulyantari, N. K., dan I wayan Putu Sutirta Yasa. (2018). Gambaran Hepatotoksisitas ( ALT / AST ) Penggunaan Obat AntiTuberkulosis Lini Pertama Dalam Pengobatan Pasien Tuberkulosis Paru Rawat Inap Di RSUP Sanglah Denpasar Tahun 2014. E_Jurnal Medika.

Kandou, P. R. D., Clarasanti, I., Wongkar, M. C. P., and Waleleng, B. J. (2016). Gambaran enzim transaminase pada pasien tuberkulosis paru yang diterapi dengan obat-obat anti tuberkulosis. Gambaran Enzim Transaminase Pada Pasien Tuberkulosis Paru Yang Diterapi Dengan Obat-Obat Anti Tuberkulosis.

Kemenkes RI. (2018). Tuberkulosis ( TB ). In Tuberkulosis.

Maelani, T., dan Cahyati, W. H. (2018). Karakteristik Penderita, Efek Samping Obat dan Putus Berobat Tuberkulosis Paru. Higeia Journal of Public Health Research and Development.

Keputusan Menteri Kesehatan RI Nomor 364/MENKES/SK/V/2009 tentang Pedoman Penanggulangan Tuberkulosis (TB), Kemente (2009).

Pontoh, L. G., Polii, E. B. I., dan Gosal, F. (2016). Gambaran kadar bilirubin pasien tuberkulosis paru selama pengobatan di RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2012 – Desember 2014. E-CliniC. https://doi.org/10.35790/ecl.4.1.2016.10834

Rosida, A. (2016). Pemeriksaan Laboratorium Penyakit Hati. Berkala Kedokteran. https://doi.org/10.20527/jbk.v12i1.364




DOI: https://doi.org/10.31983/jlm.v3i1.7917

Article Metrics

Abstract view : 158
Download PDF (Bahasa Indonesia) : 693

Refbacks

  • There are currently no refbacks.


Copyright (c) 2021 Jaringan Laboratorium Medis

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

--

OFFICE INFORMATION :

Jurusan Analis Kesehatan - Politeknik Kesehatan Kemenkes Semarang, http://analis.poltekkes-smg.ac.id Jl. Wolter Monginsidi No. 115 Pedurungan Tengah, Semarang, Jawa Tengah, Indonesia ; Telp./Fax: (024)6723014 Email: jlm@poltekkes-smg.ac.id

Statcounter  Lisensi Creative Commons Jaringan Laboratorium Medis disseminated below Creative Commons Attribution-ShareAlike 4.0 International License.

Our Related Accounts :

 

  
MoU PATELKIISSN LIPIGoogle ScholarGarudaStat CounterDOI Crossref  

 

Jaringan Laboratorium Medis © 2019