Jaringan Laboratorium Medis

Vol. 8 No. 1 (2026): May 2026
Original Articles

Correlation Analysis of Nutritional Status and Anemia in Tuberculosis Patient During Intensive and Continuation Phases

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  • Nanik Aryani Putri,
  • Teguh Budiharjo,
  • Moch. Alvin 'Izzuddin,
  • Siti Ulul Azmi
Nanik Aryani Putri
Poltekkes Kemenkes Semarang
DOI: https://doi.org/10.31983/jlm.v8i1.14723

Published 2026-05-01

Keywords

  • Tuberculosis,
  • Nutritional Status,
  • Body Mass Index,
  • Anti-Tuberculosis Drugs,
  • Anemia

How to Cite

Nanik Aryani Putri, Teguh Budiharjo, Moch. Alvin ’Izzuddin, & Siti Ulul Azmi. (2026). Correlation Analysis of Nutritional Status and Anemia in Tuberculosis Patient During Intensive and Continuation Phases. Jaringan Laboratorium Medis, 8(1), 64–73. https://doi.org/10.31983/jlm.v8i1.14723

Copyright (c) 2026 Jaringan Laboratorium Medis

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Abstract

Tuberculosis (TB) is a contagious infectious disease caused by the bacterium Mycobacterium tuberculosis, which enters the human body through the air. Treatment for tuberculosis involves Anti-Tuberculosis Drugs (OAT)—including pyrazinamide, rifampicin, isoniazid, ethambutol, and streptomycin—which may cause side effects that increase the risk of nutritional status changes and anemia. This study analyzes the relationship between nutritional status, anemia status, and the phase of treatment among TB patients in Semarang City.This research employed a descriptive observational design with a cross-sectional approach. Data were obtained from outpatient TB patients at the Bangetayu and Kedungmundu Public Health Centers (Puskesmas). A total of 44 adult subjects without comorbidities were recruited via purposive sampling, comprising 20 patients in the intensive phase and 24 in the continuation phase of treatment. Nutritional status was evaluated using Body Mass Index (BMI), while anemia status was assessed through hematological parameters, including hemoglobin (Hb), hematocrit (Ht), and erythrocyte indices. Statistical analysis revealed no significant correlation between anemia status or hematological parameters (Hb, Ht, erythrocyte indices) and BMI in either treatment group (p>0.05). These findings suggest that hematological profiles may be more heavily influenced by systemic inflammation resulting from tuberculosis (TB) infection or the effects of anti-TB therapy rather than nutritional status alone.Conversely, a significant correlation was identified between BMI and body weight (p<0.001), reflecting the inherent variations in patients' nutritional status. Future studies incorporating a larger sample size and additional variables—such as the duration of TB treatment, disease severity, and dietary intake—are warranted to further elucidate these findings. This study provides an initial contribution to understanding the link between TB, nutritional status, and anemia. Furthermore, platelets and body height showed trends toward significant differences, which may serve as a basis for further research and open opportunities for developing nutrition-based interventions for TB patients.

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