.png)
.png)
.png)
The Effect of Ciplukan Leaves Extract (Physalis minima) Effervescent Tablets as an Denture Cleanser to the Growth Candida albicans
Abstract
Denture stomatitis is one of the problems that often occurs in denture wearers. Prevention of denture stomatitis can be done by immersing the denture in a cleaning solution. Ciplukan leaves (Physalis minima) are natural ingredients that can be used for denture cleaning because they contain antimicrobials. This study aims to determine the effect of effervescent tablets of ciplukan leaf extract (Physalis minima) as a denture cleanser in inhibiting the growth of C. albicans. Methods: This type of research is a laboratory experiment with the post-test-only control group design. The sample used is acrylic resin plate made of heat curing acrylic material The samples used were 24 pieces with a size of 10x10x1 mm which were divided into 4 treatment groups. Samples were immersed in alkaline peroxide effervescent tablets and ciplukan leaf extract effervescent tablets with concentrations of 25%, 50%, and 75% for 20 minutes. The number of C. albicans colonies was counted using a spectrophotometer and converted into the formula. The results of the One-Way ANOVA statistical test showed that the number of C. albicans in each treatment group was significantly different with a significance value of 0,00. Ciplukan leaf extract effervescent tablets were able to inhibit the growth of C. albicans on heat cured acrylic resin plates with the most effective concentration of 75%.
Keywords
Full Text:
PDFReferences
N. A. Suni, V. N. S. Wowor, and M. A. Leman, “Uji Daya Hambat Rebusan Daun Pepaya (carica papaya) terhadap Pertumbuhan Candida albicans pada Plat Resin Akrilik Polimerisasi Panas,” vol. 5, no. 1, pp. 74–78, 2017.
W. Krisma, M. Mozartha, and R. Purba, “Level of Denture Cleanliness Influences the Presence of Denture Stomatitis on Maxillary Denture Bearing-Mucosa,” Jurnal of Dentistry Indonesia, vol. 21, no. 2, pp. 44–48, 2014.
G. U. Rifdayanti, I. W. Arya KF, and B. I. Sukmana, “Pengaruh Perendaman Ekstrak Batang Pisang Mauli 25% Dan Daun Kemangi 12,5% terhadap Nilai Kekasaran Permukaan,” Dentin Jurnal Kedokteran Gigi, vol. 3, no. 3, pp. 75–81, 2019.
K. Soygun, G. Bolayir, and A. Boztug, “Mechanical and thermal properties of polyamide versus reinforced PMMA denture base materials,” Journal of Advanced Prosthodontics, vol. 5, no. 2, pp. 153–160, 2013, doi: 10.4047/jap.2013.5.2.153.
K. J. Anusavice, C. Shen, and H. R. Rawls, Phillips’ Science of Dental Materials, 12th ed. Elsevier Health Sciences, 2013.
R. Garg, “Denture Hygiene, Different Strategies,” WebmedCentral DENTISTRY, vol. 1, no. 10, pp. 1–7, 2010.
A. O. Rahn, J. R. Ivanhoe, and K. D. Plummer, Textbook of Complete Dentures. . USA: PMPH, 2009.
Y. Kangsudarmanto, P. Rachmadi, and I. A. Wayan, “Perbandingan Perubahan Warna Heat Cured Acrylic Basis Gigi Tiruan yang Direndam dalam Klorheksidin dan Effervescent (Alkaline Peroxide),” Dentino J Ked Gigi, vol. 2, no. 2, pp. 205–209, 2014.
I. S. Pitojo, Ceplukan Herba Berkasiat Obat. Yogyakarta: Kanisius, 2002.
N. Anisa and L. Riniwаsih, “Formulasi dan Aktivitas Antibakteri Sediaan Obat Kumur dari Ekstrak Etanol 96% Daun Ciplukan (Physalis angulata L.) terhadap Bakteri Streptococcus mutans,” Indonesia Natural Research Pharmaceutical Journal, vol. 5, no. 2, pp. 70–82, 2020.
T. Rostikawati and L. Supratman, “Uji Antibakteri Obat Kumur Ekstrak Etanol Tanaman Ciplukan (Physalis angulata l.) Terhadap Bakteri Gram Positif,” Jurnal Pendidikan dan Biologi, vol. 13, no. 1, pp. 103–107, Dec. 2021, doi: 10.25134/quagga.v13i1.3827.
L. V. Allen, The Art, Science, and Technology of Pharmaceutical Compounding, 5th Edition, 5th ed. 2215 Constitution Avenue, N.W. Washington, DC 20037-2985: The American Pharmacists Association, 2016. doi: 10.21019/9781582122632.
U. Sharma, D. Pal, and R. Prasad, “Alkaline phosphatase: An overview,” Indian Journal of Clinical Biochemistry, vol. 29, no. 3, pp. 269–278, 2014, doi: 10.1007/s12291-013-0408-y.
I. M. de Andrade et al., “Effervescent tablets and ultrasonic devices against Candida and mutans streptococci in denture biofilm,” Gerodontology, vol. 28, no. 4, pp. 264–270, Dec. 2011, doi: 10.1111/j.1741-2358.2010.00378.x.
I. H. Setiana and A. S. W. Kusuma, “Review Jurnal: Formulasi Granul Effervescent dari Berbagai Tumbuhan,” Farmaka, vol. 16, no. 3, pp. 100–105, 2018.
M. Dhamande, A. Pakhan, R. Thombare, and S. Ghodpage, “Evaluation of efficacy of commercial denture cleansing agents to reduce the fungal biofilm activity from heat polymerized denture acrylic resin: An in vitro study,” Contemp Clin Dent, vol. 3, no. 2, pp. 168–172, Apr. 2012, doi: 10.4103/0976-237X.96820.
Wahyuni and S. Febrina Karim, “Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kacapiring (Gardenia jasminoides Ellis) terhadap Bakteri Streptococcus mutans,” Jurnal Sains Kesehatan, vol. 2, no. 4, pp. 399–404, 2020, doi: 10.25026/jsk.v2i4.191.
C. Salerno et al., “Candida-associated denture stomatitis,” Med Oral Patol Oral Cir Bucal, vol. 16, no. 2, pp. 139–143, 2011.
M. Kaczała, J. Gmyrek, Mnichowska-Polanowska, and S. Giedrys-Kalemba, “Pathomechanism of Candida infection in denture stomatitis,” Journal of Stomatology, vol. 61, no. 12, pp. 886–893, 2008.
J. M. ten Cate, F. M. Klis, T. Pereira-Cenci, W. Crielaard, and P. W. J. de Groot, “Molecular and Cellular Mechanisms That Lead to Candida Biofilm Formation,” J Dent Res, vol. 88, no. 2, pp. 105–115, Feb. 2009, doi: 10.1177/0022034508329273.
D. Bhaga and M. E. Weber, “Bubbles in viscous liquids: shapes, wakes and velocities,” J Fluid Mech, vol. 105, pp. 61–85, Apr. 1981, doi: 10.1017/S002211208100311X.
P. L. L. Walls, J. C. Bird, and L. Bourouiba, “Moving with bubbles: a review of the interactions between bubbles and the microorganisms that surround them,” Integrative and comparative biology, vol. 54, no. 6. pp. 1014–1025, Dec. 01, 2014. doi: 10.1093/icb/icu100.
A. Agarwal, H. Xu, W. J. Ng, and Y. Liu, “Biofilm detachment by self-collapsing air microbubbles: A potential chemical-free cleaning technology for membrane biofouling,” J Mater Chem, vol. 22, no. 5, pp. 2203–2207, Feb. 2012, doi: 10.1039/c1jm14439a.
H. B. Konuk and B. Ergüden, “Phenolic –OH group is crucial for the antifungal activity of terpenoids via disruption of cell membrane integrity,” Folia Microbiol (Praha), vol. 65, no. 4, pp. 775–783, Aug. 2020, doi: 10.1007/s12223-020-00787-4.
A. Prajitno, Penyakit Ikan-Udang : Bakteri. Malang: Penerbit Universitas Negeri Malang, 2007.
A. Prajitno, “Uji Sensitivitas Bio-Aktif Alami Halimeda opuntia terhadap Bakteri Vibrio harveyi secara In Vitro (Uji Patogenitas Bakteri Vibrio harveyi).,” Jurnal Penelitian Perikanan. Fakultas Perikanan Universitas Brawijaya, vol. 10, pp. 22–27, 2007.
J. E. Yun and D. G. Lee, “Role of Potassium Channels in Chlorogenic Acid-induced Apoptotic Volume Decrease and Cell Cycle Arrest in Candida albicans,” Biochim Biophys Acta Gen Subj, vol. 1861, no. 3, pp. 585–592, Mar. 2017, doi: 10.1016/j.bbagen.2016.12.026.
G. F. Ribeiro, M. Côrte-Real, and B. Johansson, “Characterization of DNA Damage in Yeast Apoptosis Induced by Hydrogen Peroxide, Acetic Acid, and Hyperosmotic Shock,” Mol Biol Cell, vol. 17, no. 10, pp. 4584–4591, Oct. 2006, doi: 10.1091/mbc.e06-05-0475.
A. Kondratskyi, K. Kondratska, R. Skryma, and N. Prevarskaya, “Ion channels in the regulation of apoptosis,” Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 1848, no. 10, pp. 2532–2546, Oct. 2015, doi: 10.1016/j.bbamem.2014.10.030.
DOI: https://doi.org/10.31983/jkg.v10i2.10868
Article Metrics
Refbacks
- There are currently no refbacks.
|  |
|
|
|
|
|
|  |  |  |  |  |  |
| View My Stats |