An Impact Inspection of Alcohol Drinks on Enzyme Levels Aspartat Aminotransferase (AST) and Alanine Aminotransferase (ALT)

Shinta Fatmawati, Yeni Vidhatul Husnah, Previta Zeizar Rahmawati

Abstract


Aspartat aminotransferase (ast) and alanine aminotransferase (Alt) or which is the enzyme transaminase used liver function tests. When alcohol enters the body, a metabolism in the liver is carried out with an end result of acetydehid when an excessive dose causes liver damage. The purpose of research to determine whether or not there is a correlation between the consumption of alcohol and its blast of bank. this study is a non-experiment of quantitative experimentation with a sampling technique. The respondents in this study are 24 alcohol drinkers of NTT students in the unfortunate city. And sample analysis methods of the kinetic ifcc and the chemical analyzer clinic - the mindray analyzer. On 24 of the respondents of all sexs-men will be analyzed based on long consumption, high consumption of alcohol, and heavy drink-alcohol consumption. The research data obtained will be done in a statistical test using the Pearson correlation test. Studies conducted on alcohol drinkers for a normal ast result are 18 respondents and abnormal results of 6. Studies on alcohol drinkers for normal test levels included 19 individuals and abnormal results for 5. The Pearson correlation test between the amount of consumption between the ast consumption is 0,184 and p-value > 0.05, and the high consumption of alcohol is 0.508 and the value of p-value 0.05, and the amount of drinking is an e-0.405 and p-value 0.05. Studies between consumption length and Alt levels have found a very weak link of 0,033 and p-value > 0.05, the high consumption of alcohol is 0,426 and the value of p-value 0.05, and the high drinking relationship of weak value are = 0.315 and p-value > 0.05. The study has had a negative impact on excessive consumption of alcohol, raising levels of ast and Alt especially on high-alcohol drinkers and excessive drinking frequency.




Keywords


AST ; ALT ; Alcoholic Drinks ; Alcohol Drinkers

Full Text:

PDF

References


Bps.go.id. (2023). Konsumsi Alkohol Oleh Penduduk Umur ≥ 15 Tahun Dalam Satu Tahun Terakhir (Liter Per Kapita), 2021-2022. Bps.Go.Id.

https://www.bps.go.id/id/statistics-table/2/MTQ3NSMy/konsumsi-alkohol-oleh-penduduk-umur--15-tahun-dalam-satu-tahun-terakhir.html

Dewi, I. T. D. P. … Merta, I. W. (2016). Kadar Serum Glutamate Piruvat Transaminase Pecandu Minuman Keras Di Banjar Ambengan Desa Sayan Ubud Gianyar. Meditory, 4(3), 82–93.

https://ejournal.poltekkes-denpasar.ac.id/index.php/M/article/view/44

Hanifah, L. N. (2023). Literature Review: Factors Affecting Alcohol Consumption and the Impact of Alcohol on Health Based on Behavioral Theory. Media Gizi Kesmas, 12(1), 453–462.

https://doi.org/10.20473/mgk.v12i1.2023.453-462

Istifara, A. … Sillehu, S. (2023). Literature Review: Pengaruh Enzim ALDH2 dalam Detoksifikasi Alkohol terhadap Sirosis Hati. Media Gizi Kesmas, 12(2), 1125–1132. https://e-journal.unair.ac.id/MGK/article/view/45573

Karlina, L. (2020). Fenomena Terjadinya Kenakalan Remaja. Jurnal Edukasi Non Formal, Vol 1 no 1(52), 147–158.

https://ummaspul.e-journal.id/JENFOL/article/view/434

Kemenkes. (2022). Intoksikasi Alkohol. https://yankes.kemkes.go.id/view_artikel/1149/intoksikasi-alkohol

Kendran, A. A. S. … Pradnyantari, A. A. S. I. (2017). Aktivitas Enzim Alanine-Aminotransferase dan Aspartate Aminotransferase pada Tikus Putih Jantan yang Diberi Ekstrak Buah Pinang. Buletin Veteriner Udayana, 9(2), 132–138.

https://ojs.unud.ac.id/index.php/buletinvet/article/download/31381/20118

Lestari, K. … Meisa, H. R. (2023). Serum Glutamc Oxaloacetic Transaminase (Sgot) and Serum Glutamic Pyruvic Transaminase (Sgpt) Values in Alcohol Drinkers. Jurnal Ilmu Kesehatan Mandira Cendikia, 2(6), 33–38.

https://journal.mandiracendikia.com/index.php/JIK-MC/article/view/306

Liana, L. T. W., & Adolf, L. L. (2019). Penyalahgunaan Konsumsi Alkohol Pada Minuman Keras Bagi Remaja Terhadap Kesehatan. STIKes Surya Mitra Husada, 9.

https://osf.io/preprints/2j795/

Maula, L. K., & Yuniastuti, A. (2017). Analisis Faktor yang mempengaruhi penyalahgunaan dan adiksi alkohol pada remaja di kabupaten pati. Public Health Perspective Journal, 2(2), 168–174.

https://journal.unnes.ac.id/nju/phpj/article/view/13587

Ozougwu, & Jevas. (2017). Physiology of the liver. International Journal of Research in Pharmacy and Biosciences, 4(8), 13–24.

https://www.researchgate.net/publication/320452275_Physiology_of_the_liver

Reza, & Rachmawati. (2017). Perbedaan Kadar SGOT dan SGPT Antara Subyek Dengan Dan Tanpa Diabetes Mellitus. Kedokteran, 6(2), 158–166.

https://ejournal3.undip.ac.id/index.php/medico/article/view/18530

Rompas, D. G. … Assa, Y. (2020). Kadar Serum Glutamate Piruvate Transaminase Pada Peminum Minuman Beralkohol di Kelurahan Tosuraya Selatan. EBiomedik, 8(1), 138–143.

https://ejournal.unsrat.ac.id/index.php/ebiomedik/article/view/28711

Sharma, P., & Arora, A. (2020). Clinical presentation of alcoholic liver disease and non-alcoholic fatty liver disease: Spectrum and diagnosis. Translational Gastroenterology and Hepatology, 5.

https://pubmed.ncbi.nlm.nih.gov/32258523/

Sijid, S. A. … Hidayat, A. S. (2020). PENGARUH PEMBERIAN TUAK TERHADAP GAMBARAN HISTOPATOLOGI HATI MENCIT (Mus musculus) ICR JANTAN. Jurnal Pendidikan Matematika Dan IPA, 11(2), 193.

https://jurnal.untan.ac.id/index.php/PMP/article/view/36623

Simanjuntak, K. (2020). Efek dari Pecandu Alkohol Terhadap Peningkatan Kerusakan Hati. Bina Widya, 23(1), 35–42.

http://library.upnvj.ac.id/pdf/artikel/Majalah_Ilmiah%20UPN/bw-vol23-no1-okt2011/35-42.pdf

Sulistiyowati, R., & Nurzhorif, F. A. (2022). Hubungan Lama Konsumsi Minuman Beralkohol Dengan Kadar Sgot Dan Sgpt Di Desa Kemojing Kecamatan Binangun Kabupaten Cilacap. Jurnal Keperawatan Dan Kesehatan Masyarakat Cendekia Utama, 11(3), 213.

https://jurnal.stikescendekiautamakudus.ac.id/index.php/stikes/article/view/985

WHO. (2024). Alcohol. https://www.who.int/news-room/fact-sheets/detail/alcohol

https://www.who.int/news-room/fact-sheets/detail/alcohol




DOI: https://doi.org/10.31983/jlm.v6i2.11777

Article Metrics

Abstract view : 75
Download PDF : 9

Refbacks

  • There are currently no refbacks.


Copyright (c) 2024 Jaringan Laboratorium Medis

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

--

OFFICE INFORMATION :

Jurusan Analis Kesehatan - Kemenkes Poltekkes Semarang, https://analis.poltekkes-smg.ac.id Jl. Wolter Monginsidi No. 115 Pedurungan Tengah, Semarang, Jawa Tengah, Indonesia ; Telp./Fax: (024)6723014 Email: jlm@poltekkes-smg.ac.id

Statcounter  Lisensi Creative Commons Jaringan Laboratorium Medis disseminated below Creative Commons Attribution-ShareAlike 4.0 International License.

Our Related Accounts :

 

  
MoU PATELKIISSN BRINGoogle ScholarGarudaStat CounterDOI Crossref  

 

Jaringan Laboratorium Medis © 2019